FOUSI supply Intermediate Synephrine CAS 94-07-5
Product Description
CAS: 94-07-5
MF: C9H13NO2
MW: 167.21
EINECS: 202-300-9
Appearance: off-white fine powder
Usage: used for rising blood pressure
Product Categories: Plant Extract
Product Parameters
Synephrine Chemical Properties
|
Melting point
|
187 °C (dec.)(lit.)
|
Boiling point
|
295.79°C (rough estimate)
|
density
|
1.1222 (rough estimate)
|
refractive index
|
1.4680 (estimate)
|
storage temp.
|
2-8°C
|
form
|
neat
|
pka
|
pKa 9.60±0.02(H2O t = 25.0±0.5 I = 0.01)(Approximate)
|
Merck
|
14,9012
|
CAS DataBase Reference
|
94-07-5(CAS DataBase Reference)
|
The most famous application of synephrine is used for the treatment of obesity. Obesity is considered a growing public health issue: more than 1 billion adults are overweight and at least 300 million people are obese[BMIP30 kg/m2]
[19]
. These situations lead to increased morbidity and mortality due to diseases such as diabetes mellitus, cardiovascular diseases, hypertension, and cancer
[19, 20]
.
Due to its affinity to a-adrenergic receptors, p-synephrine is marketed as an intravenous drug to treat hypotension
[17, 21]
. m-Synephrine has been widely employed in parenteral formulations as an intranasal decongestant
[22, 23]
, a vasopressor agent used in surgical procedures, in priapism treatment, and as a mydriatic agent
[21]
.
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