CAS 80214 -83-1 Roxithromycin Powder
Product Description
| Product name | Roxithromycin | Appearance | White or off-white crystal powder |
| CAS No. | 80214-83-1 | Odor | Odorless |
| Molecular formula | C41H76N2O15 | Density | 1.25 g/cm3 |
| Molecular weight | 837.05 | Melting point | Melting point |
| Purity | 98%,99% | Heavy metals | Less than 10ppm |
| Tesy method | HPLC | Alkalinity PH | 8.0~10.0 |
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.
Roxithromycin is available under several brandnames. Roxithromycin is not available in the United States. Roxithromycin is available in Australia. Roxithromycin has also been tested to possess antimalarial activity.
Roxithromycin is a semi-synthetic macrolide antibiotic. It is used to treat respiratory tract, urinary and soft tissue infections. Roxithromycin is derived from erythromycin, containing the same 14-membered lactone ring. However, an N-oxime side chain is attached to the lactone ring. It is also currently undergoing clinical trials for the treatment of male-pattern hair loss.
|
Items |
Requirements |
Results |
|
Appearance |
A white or almost white crystalline powder |
A white crystalline powder |
|
Specific rotation |
-82°~-87° |
-85.8° |
|
Identification (IR) |
(1)should be consistent for the trying solution prominent peak retention time with the comparison solution prominent peak retention time |
Consistent |
|
(2)this infrared light absorption atlas should be consistent with the comparison atlas |
Consistent |
|
|
related substance |
The single impurity peak area does not have to be bigger than the comparison solution prominent peak area 1.5 times |
0.9 |
|
Each miscellaneous quality area of with can not be big in check against aqua a lord the area of 4.5times |
4.2 |
|
|
Alkalinity pH |
8.0~10.0 |
9.0 |
|
Water |
less than 3.0% |
2.8% |
|
Residue on ignition |
less than 0.1% |
0.06% |
|
Heavy metals |
less than 10ppm |
less than 10ppm |
|
on the anhydrous basis |
more than 94.0% |
95.9% |
|
Conclusion |
The material conform with BP2002 |
|
Pharmaceutical Intermediate
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