99% Josamycin Vilprafen Wilprafen Josamycin Solution CAS 16846 -24-5

Model NO.
hupharma
Delivery Time
1-3 Days
Shipping
Worldwide
Minimum
10g
Payment
Bitcoin/Wu/Mg/Wire Transfer
Transport Package
Safe and Fast Delivery
Specification
10g, 100g, 1kg, 25kg
Trademark
hupharma
Origin
China
HS Code
2937290090
Production Capacity
20000kg Per Month
Reference Price
$ 0.81 - 0.90
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Product Description

99% Josamycin Vilprafen Wilprafen Josamycin Solution CAS 16846-24-5
99% Josamycin Vilprafen Wilprafen Josamycin Solution CAS 16846-24-5
99% Josamycin Vilprafen Wilprafen Josamycin Solution CAS 16846-24-5

Product Name: Josamycin
Synonyms: Vilprafen;Wilprafen;Josamycin Solution, 100ppm;Josamycin for peak identification;3-Acetate 4B-(3-Methylbutanoate)leucoMycin V;LeucoMycin V, 3-acetate4B-(3-Methylbutanoate);Leucomycin V 3-acetate 4''-(3-methylbutanoate);YL-704A3
CAS: 16846-24-5
MF: C42H69NO15
MW: 827.99
EINECS: 240-871-6

Uses:
As a 16-membered ring macrolide antibiotic with antimicrobial activity against a wide range of pathogens. Josamycin can be particularly used in the treatment of Mycoplasma infection.

Application:
A naturally occurring antibiotic produced by Streptomyces narbonensis var. josamyceticus and belonging to the leucomycin group of macrolides. It is formulated for oral administration.
Many Gram-positive and Gram-negative anaerobes are susceptible, including Peptostreptococcus spp., Propionibacterium spp., Eubacterium spp. and Bacteroides spp.

After a single 1 g oral dose, a peak serum concentration of 2.74 mg/L was achieved 0.75 h after dosing. The AUC was 4.2 mg.h/L, and the apparent elimination half-life 1.5 h. Several inactive metabolites could be detected. It penetrates into saliva, tears and sweat, and achieves high levels in bile and lungs. It is mostly metabolized and excreted in the bile in an inactive form. Less than 20% of the dose appears in the urine, producing levels of around 50 mg/L.

The drug is generally well tolerated, producing only mild gastrointestinal disturbance. Its uses are similar to those of erythromycin. It is of limited availability.



99% Josamycin Vilprafen Wilprafen Josamycin Solution CAS 16846-24-5



 

 

Pharmaceutical Intermediate

GOUV.NE, 2023