Cas:70458-92-3 Pefloxacin Antibiotic powder
product name
|
Pefloxacin
|
cas number
|
70458-92-3
|
apperance
|
white powder
|
Density
|
1.3±0.1 g/cm3
|
MF
|
C
17
H
20
FN
3
O
3
|
MW
|
333.357
|
English name: 1-ethyl-6-fluoro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
English alias: Silver Pefloxacin; Pefloxacinum; PFLX; Abactal; Pefloxacine
CAS Number: 70458-92-3
Molecular formula: C17H20FN3O3
Molecular weight: 333.35700
Accurate quality: 333.14900
PSA: 65.78000
LogP: 1.61340
Physical and chemical properties
Density: 1.32 g/cm3
Boiling point: 529.1ºC at 760 mmHg
Flash point: 273.8ºC
Refractive index: 1.593
Vapor pressure: 5.05E-12mmHg at 25°C [1]
Security Information
Dangerous goods transport code: UN 3082
Hazard category code: R51/53
Safety instructions: S61
RTECS number: WM6250000
Dangerous goods mark: N
Molecular structure data
1. Molar refractive index: 85.63
2. Molar volume (cm/mol): 252.4
3. Isotonic specific volume (90.2K): 679.3
4. Surface tension (dyne/cm): 52.4
5. Polarizability (10-24cm3): 33.94
Computational chemistry data
1. Hydrophobic parameter calculation reference value (XlogP): none
2. Number of hydrogen bond donors: 1
3. Number of hydrogen bond acceptors: 7
4. Number of rotatable chemical bonds: 3
5. Number of tautomers: none
6. Polar surface area of topological molecules 64.1
7. Number of heavy atoms: 24
8. Surface charge: 0
9. Complexity: 545
10. Number of isotope atoms: 0
11. Determine the number of atomic stereo centers: 0
12. Uncertain the number of atomic stereocenters: 0
13. Determine the number of chemical bond stereo centers: 0
14. Uncertain the number of chemical bond stereo centers: 0
15. Number of covalent bond units: 1
See Norfloxacin for clinical indications. Intravenous administration can still be used for severe cases of pulmonary infection, and it can also be used for gram-negative bacilli sepsis. The treatment of sepsis often needs to be combined with antibacterial drugs that have a synergistic effect. Used for serious infections of G-bacteria and Staphylococcus in adults such as sepsis, endocarditis, bacterial meningitis, infections of the respiratory tract, urethra, kidney, ENT, gynecological diseases, abdomen, liver and gallbladder, osteoarthritis and skin infections, etc.