Product Name
|
Gliclazide
|
CAS No.
|
21187-98-4
|
Melting point
|
163-169 °C (lit.)
|
density
|
1.2205 (rough estimate)
|
refractive index
|
1.6740 (estimate)
|
storage temp.
|
2-8°C
|
pka
|
6.07±0.10(Predicted)
|
Appearance
|
White powder
|
Grade
|
Pharmaceutical Grade
|
Gliclazide
is a 2nd generation oral sulfonylurea hypoglycemic agent with strong action. Its mechanism is similar to that of toluenosulfonylurea, i.e., it selectively acts on pancreatic β-cells to promote insuln secretion and enhance insuln release after eating glucose, which can not only improve the metabolism of diabetic patients, but also improve or delay the occurrence of diabetic vascular complications.
Gliclazide is mainly used for mild and moderate type II diabetes mellitus with adult-onset where diet and exercise control alone are ineffective and without a tendency to ketosis, and also improves fundus lesions and metabolic and vascular dysfunctions in diabetic patients.
1. For adults with type 2 diabetes, diabetes associated with obesity or vascular lesions.
2. Hypoglycemic agents. It can be used for the treatment of non-insuln dependent diabetes mellitus.