China supplier High Quality CAS 130-89-2 Quinine Hydrochloride Quinine HCl
Product Description
Quinine HCL
is a substance that was first obtained by processing the bark of the cinchona tree, a South American native plant that has been used as a fever reducer by Native Americans for centuries. This substance has been used historically to treat malaria, along with some other medical conditions, and although a number of antimalarial drugs are on the market today, it is still used in some regions. It is also used commercially as an additive to tonic water, a soft drink that is used as a mixer for other drinks in
addition to being consumed straight.
Nature Quinine is a natural white crystalline alkaloid having antipyretic (fever-reducing), antimalarial, analgesic (painkilling), anti-inflammatory properties and a bitter taste. It is a stereoisomer of quinidine which, unlike Nature Quinine, is an anti-arrhythmic. Sulphate Quinine contains two major fused-ring systems: the aromatic quinoline and the bicyclic quinuclidine.
Though it has been synthesized in the lab, the bark of the cinchona tree is the only known natural source of Nature Quinine. The medicinal properties of the cinchona tree were originally discovered by the Quechua Indians of Peru and Bolivia; later, the Jesuits were the first to bring the cinchona to Europe.
Specification
Items
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Specifications
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Appearance
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White or almost white or colourless, fine, silky needles, often in clusters
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Solubility
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Soluble in water, freely soluble in ethanol (96%).
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Identification
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A) TLC
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The principal spot in the chromatogram obtained with the test solution is similar in position, colour and size to the principal spot in the chromatogram obtained with the reference solution.
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B) Bromine and ammonia
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A green colour develops when treated with bromine water and dilute ammonia
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C) Fluorescence
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When examined in ultraviolet light at 366 nm,an intense blue fluorescence appears which disappears almost completely on the addition of 1 ml of HCL
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D) Characteristic of chlorides
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It gives the reactions of chlorides
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E) Test for pH
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Should comply
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Appearance of solution
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Solution S is clear and not more intensely coloured than reference solution GY6
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pH
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6.0~6.8
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Specific optical rotation
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-245° ~ -258°
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Other cinchona alkaloids
Impurity C
Any impurity eluted before quinine
Any other impurity
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NMT 10%
NMT 5%
NMT 2.5%
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Sulphates
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NMT 500ppm
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Barium
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Should comply
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Loss on drying
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6%~10%
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Sulphated ash
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NMT 0.1%
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Assay
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99.0 %-101.0 % on dried substance
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Packing & Delivery
For small samples quantity <1 kilograms, inside we use double resealable zip bags and outside with aluminium Foil Bags.
For medium quanity 1-25 kilograms, inside we use double resealable zip bags and outside with aluminium Foil Bags, then packed in cartons or small drums for shipping.
For larger quanity >25 kilograms, inside we use double resealable zip bags and outside with aluminium Foil Bags OR bigger size double seal PET bags for 25kgs in bulk then packed in drums for shipping.
Please contact us for more details if you have any question!
Our Company
Crovell
Crovell is a fast growing intermediates company,Which located in Shijiazhuang,Hebei Province.
So far, Crovell has business in more than 35 countries,most big customers come from europe and America, because among the suppliers in china,Crovell can always make the product quality best, most of products from Crovell can reach the purity of 99.9+,the important reason for customers who choosing Crovell.
Certifications
Exhibition
Our Service
1. Quality control, before shipment, free sample for test. after shipment, keep sample for 3 years
2. Prompt shipment with professional documents
3. Packing as your request, with photo before shipment.
FAQ
Q1.
Can I have a sample order for your products?
A: Yes, we welcome sample order to test and check quality. Mixed samples are acceptable.
Q2.
What about the lead time?
A:Sample needs 3-5 days, mass production time needs 1-2 weeks for order quantity more than
Q3.
Do you have any MOQ limit for order?
A: Low MOQ, 10-100g for sample checking is available
Q4.
How do you ship the goods and how long does it take to arrive?
A: We usually ship by DHL, UPS, FedEx or TNT. It usually takes 3-5 days to arrive. Airline and sea shipping also optional.
Q5.
How to proceed an order for your products?
A: Firstly let us know your requirements or application.
Secondly We quote according to your requirements or our suggestions.
Thirdly customer confirms the samples and places deposit for formal order.
Fourthly We arrange the production.
Q6.
Is it OK to print my logo on package?
A: Yes. Please inform us formally before our production and confirm the design firstly based on our sample.
If you have any other needs, please contact me.