Introduction of Quinine
1. Quinine Sulphate is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
2. Quinine Sulphate is a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
3. Quinine Sulphate is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
Application of
Quinine
1.An alkaloid derived from the bark of the cinchona tree.
2.It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633.
3.Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose.
4.It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis.
5.Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
Quinine
Details
Product Name: | Quinine sulfate dihydrate |
Synonyms: | Quinine sulfate fluorescence standard substance;QUININE SULPHATE 2H2O;Quinine sulfate hydrate |
CAS: | 6119-70-6 |
MF: | C20H26N2O6S |
MW: | 422.5 |
EINECS: | 639-128-2 |
Product Categories: | API;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Herb extract |
Mol File: | 6119-70-6.mol |
Melting point | ~225 °C (dec.)(lit.) |
alpha | -245 º (c=2, 0.1M HCl) |
FEMA | 2977 | QUININE SULFATE |
storage temp. | Keep in dark place,Sealed in dry,2-8°C |
form | Crystalline Powder |
color | Light yellow or beige to brown |
Water Solubility | 0.12 g/100 mL (20 ºC) |
Sensitive | Light Sensitive |
Merck | 14,8061 |
BRN | 6113937 |
Stability: | Stable. Incompatible with strong oxidizing agents |
CAS DataBase R | 6119-70-6(CAS DataBase Reference) |
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