Product name: Glucagon
Alias: Glucagon Acetate; Glucagon1-37
CAS No.: 16941-32-5
Molecular Formula: C153H225N43O49S
Molecular Weight: 3482.75
Purity (by HPLC): โฅ98.0%
Appearance: White powder
EINECS: 204-035-4
Grade: Pharmceutical Grade
Storage: Shading, confined preservation
Usage: Glucagon generally elevates the concentration of glucose in the blood by promoting gluconeogenesis and glycogenolysis
Glucagon is a peptide hormone, produced by alpha cells of the pancreas, it raises the concentration of glucose in the bloodstream. Its effect is opposite that of insuli, which lowers the glucose concentration. The pancreas releases glucagon when the concentration of glucose in the bloodstream falls too low. Glucagon causes the liver to convert stored glycogen into glucose, which is released into the bloodstream. High blood Glucose levels stimulate the release of insuli. Insuli allows glucose to be taken up and used by insuli-dependent tissues. Thus, glucagon and insuli are part of a feedback system that keeps blood glucose levels at a stable level. Glucagon belongs to a family of several other related hormones.
Glucagon is also known as glucagon or anti insuli or insuli B. It is accompanied by a hormone insuli secretion from pancreatic islet alpha cells of vertebrates. Confrontation and insuli plays a role, increase blood glucose. In 1953, was isolated by precipitation and obtain the crystallization. It is based on the N- terminal histidine as a starting point, C terminal threonine is a single chain peptide terminus of 29 amino acids (molecular weight is about 3500), does not have the S-S bonds in a molecule, at this point, completely different from insuli. The structure of the compound has been synthesized by chemical recent affirmation. The early effect of glucagon process is specific binding exists in the target cell receptors on the cell membrane, the adenylate cyclase activation, ring type AMP as the second messenger activating phosphorylase, promoting glycogenolysis.
In contrast to the action of insuli, glucagon is a promoting hormone catabolism. Glucagon has very strong promoting glycogenolysis and gluconeogenesis, make the blood glucose increased significantly, 1mol/L hormone can make 3 x 106mol/L glucose from glycogen decomposed rapidly out. Glucagon by cAMP-PK system, the activation of hepatic cells accelerated glycogen phosphorylase, decomposition. Gluconeogenesis is enhanced because hormone accelerate amino acids into liver cells, and activate the enzyme of gluconeogenesis.
Glucagon also activates lipase, promote fat decomposition, and can enhance the oxidation of fatty acid, so that increased ketogenesis. The target organ of glucagon produced the metabolic effects of the liver, liver resection or interruption of hepatic blood flow, these effects disappeared.
In addition, the secretion of glucagon may promote insuli and islet somatostatin. Pharmacological doses of glucagon can make the content of cAMp in myocardial cells increased, myocardial contraction enhancement.
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Generic Peptides | CAS No . | Application |
Semaglutide | 910463-68-2 | Diabetes Mellitus |
Liraglutide | 204656-20-2 | Diabetes Mellitus |
Albiglutide | 782500-75-8 | Diabetes Mellitus |
Beinaglutide | 123475-27-4 | Dlabetes Mellitus |
Dulaglutide | 923950-08-7 | Diabetes Mellitus |
Exenatide | 141732-76-5 | Diabetes Mellitus |
Lixisenatide | 320367- 13-3 | Diabetes Mellitus |
Tirzepatide | 2023788- 19-2 | Diabetes Mellitus & others |
( Arg 8)- Vasopressin | 11000- 17-2 | Diabetes Insipidus |
Abarelix (acetate) | 183552-38-7 | Oncology |
Alarelin Acetate (GnRH a gonist) | 79561-22- 1 | Women's health |
Bivalirudin (trifluor oacetate) | 128270-60-0( net ) | Cardiovascular Disease |
1607799- 13-2 ( acetate ) | Male health | |
Busereli | 57982-77- 1 ( net ) | Oncology, Reproductive Medicine |
68630-75- 1 ( acetate ) | ||
Calcitonin (salmon) | 47931-85- 1 | Paget's disease, Hyp ercalcemnia and Osteoporosis |
Carbetocin Acetate | 37025-55- 1 | Women's health |
Copper Peptide GHK-Cu (acetate) | 300801-03-0 | Anti-aging |
Degarelix | 214766-78-6 | Prostatic diseases |
DSIP Delta sleep-inducin g peptide | 62568-57-4 | |
Epithalon | Anti-aging | |
Glucagon | 16941-32-5 | Diabetes Mellitus |
Gonadoreli Acetate | 33515-09-2 ( net ) | Oncology, Reproductive Medicine |
34973-08-5 ( acetate ) | ||
Goserelim Acetate | 65807-02-5 ( net ) | Oncology, Reproductive Medicine |
145781-92-6 ( acetate ) | ||
Icatibant Acetate | 130308-48-4( net ) | Hereditary Angioedema |
138614-30-9 ( acetate ) | ||
Kisspeptin ( KP - 10) | 374675-21-5 | Cancer & Apoptosis, Hormones, Neuroscience |
Leuprolide; Leuprore li n Acetate | 53714- ยท56-0 ( net ) | Oncology |
74381-53-6 ( acetate ) | ||
Melanotan II | 121062-08-6 | Male bealth |
Nafareli n | 86220-42-0 | Women's health |
Octreotide (acetate) | 83150-76-9 ( net ) | Oncology |
79517-01-4 ( acetate ) | ||
Oxytocin Acetate | 6233-83ยท6 | Cardiovascular Disease |
Pentagastrin | 5534-95-2 | Gastrointestinal |
Pramlintide (acetate hydrate) | 196078-30-5 | Diabetes Mellitus |
Selank ( acetate ) | 129954-34-3 | Immunology |
Semax ACT H (4-7) | 80714-61-0 | Nootropics |
Seractide ( ACT H ( 1-39) Porcine ) | 12279-41-3 | Immunology |
Sincalide | 25126-32-3 | Gallbladder diseases |
Somatostatin (acetate) | 38916-34-6 ( net ) | Gastrointestinal |
Taltirelin ( TA -5910) | 1549593-23-8 | SCD |
Teduglutide | 197922-42-2 | SBS |
Teriparatide pTH ( 1-34) Acetate | 52232-67-4 ( net ) | Osteoporosis |
99294-94-7 ( acetate ) | ||
Tetracosactide (Cosyn tropin) | 16960- 16-0 (net) | Oncology, Diagnostics |
60189-34-6( acetate ) | ||
Thymalfasin ; Thymosin Alpha - 1 ( acetate ) | 62304-98-7 | CHB; Immunology |
Thymopentin TP -5 ( acetate ) | 69558-55-0 | Immunology |
Thymosin Beta -4 ( acetate ) | 77591-33/4 | Oncology |
Vyleesi (acetate) | 1607799- 13-2 | Women's health |
Setmelanotide |
Dongdu biology co., ltd
is a professional production of Chemical Products.
The company was established in 2000, the company actively explore overseas markets.
The company's main products are
Procain e,Pmk,Xylazine HCl,Tianeptine Sodium Salt,BMK,PMK,Lidocain e,(2-Bromoethyl)Benzene,Pharmaceutical Intermediates,Chemical Raw Materials,Iodine
The products are mainly exported to North America, South USA, Europe, Australia, the Middle East, Southeast Asia Africa, etc..
Our company mainly production workshop covers an area of 16000 square meters, 10000 square meters factory in.
We are from China and the top machinery imported from domestic manufacturers of machinery and equipment, facilities.
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As we built, we keep "quality policy, the pursuit of perfection, sincere service".
Through this policy, we provide high quality products and the best service for customers.
Our goal is to make progress, with the best value for their money to our customers.
As a result, we have gained great reputation from our customers.
We welcome you warmly inquiries.
We guarantee, sincere service, high quality products and competitive price.
1. Quality
Our products meet msds safe standard and we have iso and other certificate so yan can get high quality products from our company.
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We can do according to the customers' request.
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EMS, DHL, TNT, UPS ,FEDEX, by air, by sea
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