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Manufacturer Supply Large Quantity Cinchona Extracat High Quality 99% CAS 56-54-2 Quinidine
Model NO.
TY-02AL
Einecs
612-097-2
Shelf
2 Years
Assay
99%
Appearance
White Powder
CAS No.
56-54-2
Transport Package
25kg/Drum 1kg, 10kg, 100kg, 200kg
Specification
25kg/drum
Trademark
tongyon
Origin
China
Production Capacity
5000kg/Month
Reference Price
$ 72.00 - 108.00
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Description
Product Description
Product name
Quinidine
CAS
56-54-2
Appearance
white powder
Assay
99%
Storage
Cool and Protect from light
Product Name:Quinidine
CAS:56-54-2
MF:C20H24N2O2
MW:324.42
EINECS:200-279-0
Mol File:56-54-2.mol Melting point:168-172 °C(lit.)
alpha 256 º (c=1, EtOH)
Boiling point:462.75°C (rough estimate)
Density 1.1294 (rough estimate)
refractive index 1.5700 (estimate)
storage temp. Store at -20°C
pka5.4, 10.0(at 20ºC)
form Powder
color White to off-white
optical activity[α]20/D +265±5°, c = 0.8% in ethanol (dry matter)
Water Solubility 0.05 g/100 mL (20 ºC)
Sensitive Light Sensitive
Description
Quinidine is a commonly used class I antiarrhythmic drug. It is a stereoisomer of quinine, originally derived from the bark of the cinchona tree. It exerts its antiarrhythmic effects on the heart by interacting with the electrophysiology mechanisms that cause arrhythmias to modify the abnormalities in impulse initiation and conduction. Quinidine depresses normal automaticity in cardiac fibers that may act as ectopic pacemakers causing arrhythmias. Quinidine also blocks the slowly inactivating, tetrodotoxin-sensitive Na current, the slow inward calcium current (ICa), the rapid (IKr) and slow (IKs) components of the delayed potassium rectifier current, the inward potassium rectifier current (IKI), the ATP-sensitive potassium channel (IKATP) and Ito.
Chemical Propertieswhite to light yellow crystal powde
UsesA dextrorotatory stereoisomer of Quinine. Antiarrhythmic (class IA). Antimalarial
Usesantiarrhythmic, antimalarial
UsesQuinidine occurs in cinchona bark to about0.25-0.3% and also in cuprea bark. It is present in quinine sulfate mother liquor. Itis formed by isomerization of quinine. Itis used in the prevention of certain cardiacarrhythmias.
GuangZhou TongYi biochemistry technology Co., Ltd is a company specializing in active pharmaceutical ingredient
(API), biology, plant extracts, chemical raw materials, fine chemicals, pharmaceutical intermediates, cosmetics raw
material. Our company has always adhered to the company philosophy of integrity, professionalism, quality first, and
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customers with efficient services,
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Our company focuses on the future and the world, and will continue to devote itself to technological progress and the
development of new products in the future, hoping to work hand in hand with new and old friends at home and abroad
to create a better future.
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